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Task

Exploring Abalone Bio's Offerings

As a potential collaborator or investor interested in biotechnology innovations, I explore the available platforms, pipelines, and partnerships, so that I can evaluate Abalone Bio's capabilities and potential for collaboration or investment.

Success definition: Given I am on the Abalone Bio website homepage When I click on the 'Platform' link, then navigate to the 'Pipeline', and finally to the 'Partnerships' page Then I should see detailed information regarding Abalone Bio's antibody platform, current projects in the pipeline, and collaboration opportunities with the company.

Trajectory

Step 1:

Url (before/after):

https://www.abalonebio.com/

https://www.abalonebio.com/platform

Content (before/after): 

RootWebArea Abalone Bio | Home, focused, url='https://www.abalonebio.com/'
    banner
        [53] link Abalone Bio Abalone Bio, center=(468,36), url='https://www.abalonebio.com/'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a08_iconlogo-default.svg'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a07_iconlogo-hover.svg'
Show more 
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a06_iconlogo-click.svg'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a04_wordmark.svg'
        navigation
            [61] link Platform, center=(1203,36), url='https://www.abalonebio.com/platform'
            [62] link Pipeline, center=(1302,36), url='https://www.abalonebio.com/pipeline'
            [63] link Partnerships, center=(1414,36), url='https://www.abalonebio.com/partnerships'
            [64] link News, center=(1519,36), url='https://www.abalonebio.com/media'
    heading Unleashing therapeutic biology
    StaticText The Challenge
    heading Creating antibody activators for key disease targets
    StaticText Target Challenge
    heading Key targets lack drugs
    paragraph
        StaticText Millions of patients remain untreated because drug discovery has failed to deliver therapeutics for many key disease targets.
    StaticText Drug Challenge
    heading Existing drugs lack specificity
    paragraph
        StaticText Small molecules or peptides often have off-target interactions, resulting in intolerable side effects.
    StaticText Antibody Challenge
    heading Antibodies are specific 
but lack activity
    paragraph
        StaticText Antibodies can recognize their targets with exquisite specificity. However, it has been a very difficult task to find activators.
    image Proteins over membrane, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a5d_proteins-and-membrane.svg'
    image Stylized light blue letter "W" with whimsical curls on a black background., url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f3e06425009c8b6a0779a_Graphic-01.svg'
    image Antibody, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a5f_antibody-blues.svg'
    image Protein, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a5e_Group%2032.svg'
    image Blue proteins, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f412f2e2556332b634987_Graphic-01go.svg'
    StaticText How are we different?
    heading We create target-activating antibodies that unlock key challenging disease targets
    StaticText FAST
    paragraph
        StaticText We have developed our Functional Antibody Selection Technology (FAST) platform to rapidly create difficult-to-discover antibody activators for challenging and promising target classes. We focus first on key G-protein coupled receptors (GPCRs), which play a role in regulating nearly every biological area.
    heading What makes us different?
    heading We tackle GPCRs, the hardest target class for antibodies
    paragraph
        StaticText Unlike other target classes, which can be activated through dimerization or clustering, GPCRs require precise adjustments to their protein structures to activate or modulate them.
    image Kidney, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a34_kidney.svg'
    image Brain, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a35_brain.svg'
    image GPCR, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a37_GPCR_icon.svg'
    image Heart, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a36_hearth.svg'
    image Stomach, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a33_stomach.svg'
    image 100 million, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a39_100-million.svg'
    heading We measure function not just binding: 100M antibodies at once, 100X more than others
    paragraph
        StaticText We biologically measure individual antibodies for activity in a massively parallel fashion with our engineered yeast cells that link cell survival to antibody functional against a target.
    heading We have enabled AI to predict activating antibodies, a first in the field
    paragraph
        StaticText We don’t only discover rare activators. Our large, proprietary activity datasets pave the path to AI-guided antibody design.
    image Protein and antibody, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a60_center-ai.svg'
    image Computer, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a61_Isolation-Mode.svg'
    StaticText Only
    image Antibody, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f9c19d333eaa348215364_Group%20272.svg'
    StaticText 6 GPCR
    StaticText have had antibody activators discovered for them.
    image Row of 3D grey and blue cylindrical shapes representing data or sound waves., url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f9b98279c554824eb30f9_Group%20275.svg'
    StaticText Abalone Bio
    StaticText has unlocked
    image Antibody, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f9c600980afe10ab34ed8_Group%20269.svg'
    StaticText 2 of them
    heading It's not just an idea. We've already done it twice
    paragraph
        StaticText We’ve built and derisked the platform and are currently creating activating antibodies for our internal pipeline and our partners.
    heading Our leadership team
    heading Discovering the next generation of antibody drugs
    list
        listitem
            StaticText Richard Yu, PhD
            StaticText CEO and Co-Founder
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        listitem
            StaticText Toshi Takeuchi, PhD
            StaticText CSO
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        listitem
            StaticText Monica Schwartz, PhD
            StaticText VP of Antibody Discovery
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        listitem
            StaticText Lauren Schwimmer
            StaticText VP of Preclinical Development
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        listitem
            StaticText Sameer Soi
            StaticText VP of data science & AI
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
    heading Overview
    link Platform We have harnessed nature's "survival of the fittest" to test hundreds of millions of antibodies for activity, not just binding, in parallel. Arrow right, url='https://www.abalonebio.com/platform'
        heading Platform
        image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
    link Pipeline We are focused on diseases impacting millions of lives that can uniquely be addressed with target-activating antibodies. Arrow right Arrow right, url='https://www.abalonebio.com/pipeline'
        heading Pipeline
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
    link Partnerships We are working with top drug companies to bring them target-activating antibodies for their key targets. Learn more about collaborating with Abalone Bio. Arrow right Arrow right, url='https://www.abalonebio.com/partnerships'
        heading Partnerships
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
    contentinfo
        StaticText Newsroom
        heading Press inquires
        StaticText Excited to share our story! Connect with us at the email below for media inquiries.
        link press@abalonebio.com Arrow right Arrow right, url='mailto:press@abalonebio.com?subject=Contact%20from%20website'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        link Home page, url='https://www.abalonebio.com/'
            image Home page, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899d1_iconlogo-footer.svg'
        StaticText Abalone Bio
        StaticText 1250, 45st. Ste 520,
        StaticText Emeryville, CA, USA, 94608
        link Platform, url='https://www.abalonebio.com/platform'
        link Pipeline, url='https://www.abalonebio.com/pipeline'
        link Partnerships, url='https://www.abalonebio.com/partnerships'
        link LinkedIn, url='https://www.linkedin.com/company/abalone-bio-inc/'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899cd_icon-linkedin.svg'
        link A product by Codon65 A product by Codon65, url='https://www.codon65.com/'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a59_sign-default.svg'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a58_sign-hover.svg'
        StaticText Abalone Bio © All rights reserved.
        StaticText ©
        StaticText 2024

RootWebArea Abalone Bio | Platform, focused, url='https://www.abalonebio.com/platform'
    banner
        [48] link Abalone Bio Abalone Bio, center=(468,36), url='https://www.abalonebio.com/'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a08_iconlogo-default.svg'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a07_iconlogo-hover.svg'
Show more 
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a06_iconlogo-click.svg'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a04_wordmark.svg'
        navigation
            [56] link Platform, center=(1203,36), url='https://www.abalonebio.com/platform'
            [57] link Pipeline, center=(1302,36), url='https://www.abalonebio.com/pipeline'
            [58] link Partnerships, center=(1414,36), url='https://www.abalonebio.com/partnerships'
            [59] link News, center=(1519,36), url='https://www.abalonebio.com/media'
    heading Platform
    heading Enabling discovery and design of target-activating antibodies through large-scale activity measurement
    paragraph
        StaticText Abalone Bio's FAST platform leverages engineered cells to evaluate hundreds of millions of antibodies simultaneously, assessing their ability to modify the activity of a target rather than merely binding to it. By producing extensive sequence-activity datasets, FAST not only uncovers rare activators for challenging targets like G-protein-coupled receptors but also enables their AI-powered design.
    StaticText The problem
    heading Lack of large-scale activity measurement was a major roadblock to target-activating antibodies
    paragraph
        StaticText The lack of large-scale activity measurement has been a significant obstacle in creating target-activating antibodies, particularly for GPCRs and other membrane proteins. These targets present unique challenges.
    heading Why are GPCRs and other membrane targets hard?
    image Proteins graphics, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a20_problem-12x.png'
    heading Proteins are hard to produce
    paragraph
        StaticText Many in vitro discovery methods require large amounts of homogenous, properly folded protein. GPCRs are complex membrane proteins that are difficult to produce and purify.
    image Target-activating antibodies, particularly for GPCRs and other membrane proteins, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a1f_problem-22x.png'
    heading Limited accessibility
    paragraph
        StaticText GPCRs are embedded in cell membranes, exposing limited extracellular portions for antibody interaction.
    image GPCRs embedded in cell membranes, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a1e_problem-32x.png'
    heading Complexity underlying activation
    paragraph
        StaticText The lack of large-scale activity measurement has been a significant obstacle in creating target-activating antibodies, particularly for GPCRs and other membrane proteins. These targets present unique challenges:
    StaticText The solution
    heading Introducing FAST
    paragraph
        StaticText our Functional Antibody Selection Technology platform
    paragraph
        StaticText Measuring activity, not just binding, in high-throughput by harnessing “survival of the fittest” with engineered biology.
    heading We harness Nature’s original algorithm
    StaticText We have engineered cells to each measure the activity of a single antibody sequence variant - a massively parallel biological computer.
    heading Engineering FAST cells to proliferate if carrying a functional antibody
    StaticText We engineer each of FAST’s yeast cells- a synthetic biology workhorse eukaryotic organism similar to a simplified human cell- to produce a functional human target protein and a single antibody variant per cell.
    heading Enabling discovery and creation of rare functional antibodies with large-scale functional datasets
    StaticText We produce growth curves that reflect function for hundreds of millions of antibody sequences. These data are mined to discover rare hits in large antibody libraries, and to train protein LLMs to extrapolate into novel sequence space to create optimized hits.
    heading Our FAST platform addresses fundamental challenges in antibody discovery and design, paving the way for breakthroughs for previously intractable targets.
    heading The conventional focus on affinity 
is flawed
    StaticText Affinity
    StaticText Activity
    heading Our technology directly measures activity of all antibodies, eliminating biases from binding-based methods
    paragraph
        StaticText Existing large-scale discovery technologies focus on attributes like binding affinity first, largely because that is historically an easy property to score and optimize.
        StaticText Activity is tested very late in the discovery process on a few high-affinity antibodies targeting regions that may have nothing to do with altering the activity of the target. It’s like tightly grabbing a pair of scissors by the blades instead of more loosely by the handle- a high affinity but non-functional interaction.
    heading Our large-scale activity datasets unlock the power of AI for activating antibody design
    paragraph
        StaticText Other AI methods use static protein structures to attempt binding prediction, falling short for predicting activating binders for dynamic, large, complex membrane targets like GPCRs. FAST broadly samples the experimental landscape of antibody activity.
        StaticText One FAST campaign generates activity datasets nearly 10X bigger than sequence datasets used to train class-leading antibody foundation models. By combining pre-trained antibody language models and our datasets, we enable model-enriched discovery and generative design of more active, developable antibodies.
    contentinfo
        StaticText Newsroom
        heading Press inquires
        StaticText Excited to share our story! Connect with us at the email below for media inquiries.
        link press@abalonebio.com Arrow right Arrow right, url='mailto:press@abalonebio.com?subject=Contact%20from%20website'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        link Home page, url='https://www.abalonebio.com/'
            image Home page, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899d1_iconlogo-footer.svg'
        StaticText Abalone Bio
        StaticText 1250, 45st. Ste 520,
        StaticText Emeryville, CA, USA, 94608
        link Platform, url='https://www.abalonebio.com/platform'
        link Pipeline, url='https://www.abalonebio.com/pipeline'
        link Partnerships, url='https://www.abalonebio.com/partnerships'
        link LinkedIn, url='https://www.linkedin.com/company/abalone-bio-inc/'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899cd_icon-linkedin.svg'
        link A product by Codon65 A product by Codon65, url='https://www.codon65.com/'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a59_sign-default.svg'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a58_sign-hover.svg'
        StaticText Abalone Bio © All rights reserved.
        StaticText ©
        StaticText 2024

Reasoning for action: By clicking on the 'Platform' link, I advance my exploration of Abalone Bio's capabilities in biotechnology. This is the first step in the user's journey, as detailed information about the platform is essential to assess their innovations and potential for collaboration or investment.

Action: click('61') # Click on the 'Platform' link to explore more about their platform.

Change Description: The browser navigated from the home page of Abalone Bio to the dedicated 'Platform' page, updating the page title and content features to focus on the FAST platform, including headings and paragraphs that detail the technology and its capabilities, alongside a change in the navigation and focus state of the links.

Screenshot before:Screenshot after:---

Step 2:

Url (before/after):

https://www.abalonebio.com/platform

https://www.abalonebio.com/pipeline

Content (before/after): 

RootWebArea Abalone Bio | Platform, focused, url='https://www.abalonebio.com/platform'
    banner
        [48] link Abalone Bio Abalone Bio, center=(468,36), url='https://www.abalonebio.com/'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a08_iconlogo-default.svg'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a07_iconlogo-hover.svg'
Show more 
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a06_iconlogo-click.svg'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a04_wordmark.svg'
        navigation
            [56] link Platform, center=(1203,36), url='https://www.abalonebio.com/platform'
            [57] link Pipeline, center=(1302,36), url='https://www.abalonebio.com/pipeline'
            [58] link Partnerships, center=(1414,36), url='https://www.abalonebio.com/partnerships'
            [59] link News, center=(1519,36), url='https://www.abalonebio.com/media'
    heading Platform
    heading Enabling discovery and design of target-activating antibodies through large-scale activity measurement
    paragraph
        StaticText Abalone Bio's FAST platform leverages engineered cells to evaluate hundreds of millions of antibodies simultaneously, assessing their ability to modify the activity of a target rather than merely binding to it. By producing extensive sequence-activity datasets, FAST not only uncovers rare activators for challenging targets like G-protein-coupled receptors but also enables their AI-powered design.
    StaticText The problem
    heading Lack of large-scale activity measurement was a major roadblock to target-activating antibodies
    paragraph
        StaticText The lack of large-scale activity measurement has been a significant obstacle in creating target-activating antibodies, particularly for GPCRs and other membrane proteins. These targets present unique challenges.
    heading Why are GPCRs and other membrane targets hard?
    image Proteins graphics, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a20_problem-12x.png'
    heading Proteins are hard to produce
    paragraph
        StaticText Many in vitro discovery methods require large amounts of homogenous, properly folded protein. GPCRs are complex membrane proteins that are difficult to produce and purify.
    image Target-activating antibodies, particularly for GPCRs and other membrane proteins, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a1f_problem-22x.png'
    heading Limited accessibility
    paragraph
        StaticText GPCRs are embedded in cell membranes, exposing limited extracellular portions for antibody interaction.
    image GPCRs embedded in cell membranes, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a1e_problem-32x.png'
    heading Complexity underlying activation
    paragraph
        StaticText The lack of large-scale activity measurement has been a significant obstacle in creating target-activating antibodies, particularly for GPCRs and other membrane proteins. These targets present unique challenges:
    StaticText The solution
    heading Introducing FAST
    paragraph
        StaticText our Functional Antibody Selection Technology platform
    paragraph
        StaticText Measuring activity, not just binding, in high-throughput by harnessing “survival of the fittest” with engineered biology.
    heading We harness Nature’s original algorithm
    StaticText We have engineered cells to each measure the activity of a single antibody sequence variant - a massively parallel biological computer.
    heading Engineering FAST cells to proliferate if carrying a functional antibody
    StaticText We engineer each of FAST’s yeast cells- a synthetic biology workhorse eukaryotic organism similar to a simplified human cell- to produce a functional human target protein and a single antibody variant per cell.
    heading Enabling discovery and creation of rare functional antibodies with large-scale functional datasets
    StaticText We produce growth curves that reflect function for hundreds of millions of antibody sequences. These data are mined to discover rare hits in large antibody libraries, and to train protein LLMs to extrapolate into novel sequence space to create optimized hits.
    heading Our FAST platform addresses fundamental challenges in antibody discovery and design, paving the way for breakthroughs for previously intractable targets.
    heading The conventional focus on affinity 
is flawed
    StaticText Affinity
    StaticText Activity
    heading Our technology directly measures activity of all antibodies, eliminating biases from binding-based methods
    paragraph
        StaticText Existing large-scale discovery technologies focus on attributes like binding affinity first, largely because that is historically an easy property to score and optimize.
        StaticText Activity is tested very late in the discovery process on a few high-affinity antibodies targeting regions that may have nothing to do with altering the activity of the target. It’s like tightly grabbing a pair of scissors by the blades instead of more loosely by the handle- a high affinity but non-functional interaction.
    heading Our large-scale activity datasets unlock the power of AI for activating antibody design
    paragraph
        StaticText Other AI methods use static protein structures to attempt binding prediction, falling short for predicting activating binders for dynamic, large, complex membrane targets like GPCRs. FAST broadly samples the experimental landscape of antibody activity.
        StaticText One FAST campaign generates activity datasets nearly 10X bigger than sequence datasets used to train class-leading antibody foundation models. By combining pre-trained antibody language models and our datasets, we enable model-enriched discovery and generative design of more active, developable antibodies.
    contentinfo
        StaticText Newsroom
        heading Press inquires
        StaticText Excited to share our story! Connect with us at the email below for media inquiries.
        link press@abalonebio.com Arrow right Arrow right, url='mailto:press@abalonebio.com?subject=Contact%20from%20website'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        link Home page, url='https://www.abalonebio.com/'
            image Home page, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899d1_iconlogo-footer.svg'
        StaticText Abalone Bio
        StaticText 1250, 45st. Ste 520,
        StaticText Emeryville, CA, USA, 94608
        link Platform, url='https://www.abalonebio.com/platform'
        link Pipeline, url='https://www.abalonebio.com/pipeline'
        link Partnerships, url='https://www.abalonebio.com/partnerships'
        link LinkedIn, url='https://www.linkedin.com/company/abalone-bio-inc/'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899cd_icon-linkedin.svg'
        link A product by Codon65 A product by Codon65, url='https://www.codon65.com/'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a59_sign-default.svg'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a58_sign-hover.svg'
        StaticText Abalone Bio © All rights reserved.
        StaticText ©
        StaticText 2024

RootWebArea Abalone Bio | Pipeline, focused, url='https://www.abalonebio.com/pipeline'
    banner
        [50] link Abalone Bio Abalone Bio, center=(468,36), url='https://www.abalonebio.com/'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a08_iconlogo-default.svg'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a07_iconlogo-hover.svg'
Show more 
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a06_iconlogo-click.svg'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a04_wordmark.svg'
        navigation
            [58] link Platform, center=(1203,36), url='https://www.abalonebio.com/platform'
            [59] link Pipeline, center=(1302,36), url='https://www.abalonebio.com/pipeline'
            [60] link Partnerships, center=(1414,36), url='https://www.abalonebio.com/partnerships'
            [61] link News, center=(1519,36), url='https://www.abalonebio.com/media'
    heading Pipeline
    heading Multiple disease areas uniquely unlocked by activating antibodies
    paragraph
        StaticText Our specific, activating antibodies address the liabilities of other drugs for challenging targets: they have the specificity that small molecules and peptides often don’t, and the activity that other antibodies typically lack. Antibodies have long half-lives, unlike some small molecules and peptides, making them very effective for chronic conditions. Antibodies also have the chemical and large structural complexity to better mimic large ligands, like chemokines, and interact with multiple parts of the target for effective activation.
    StaticText Specifically activate targets and target subpopulations to increase efficacy and reduce intolerable side effects
    StaticText ‍
    StaticText Activate hypertrophy to combat muscle loss during weight loss.
    StaticText Metabolic
    image Arrow, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a09_arrow-up.svg'
    StaticText Inflammation
    image Arrow, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a09_arrow-up.svg'
    StaticText Activate wound-healing to address disease causes, not just treat symptoms
    StaticText ‍
    StaticText Allosterically activate hydrophobic ligand responsive receptors from the outside of the cell, sidestepping problems of  hydrophobic drugs that bind orthosterically.
    StaticText Cancer
    image Arrow, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a09_arrow-up.svg'
    [104] div, center=(960,897), inner_text=Activate wound-healing to address disease causes, not just treat symptoms
‍
Allosterically activate hydrophobic ligand responsive receptors from the outside of the cell, sidestepping problems of  hydrophobic drugs that bind orthosterically.
    StaticText Locally recruit and activate tumor-killing T cells to tumors with chemokine receptor activators
    StaticText ‍
    StaticText Activate receptor internalization to expand the therapeutic windows of ADCs.
    StaticText Pipeline
    heading We have performed multiple discovery campaigns for partners and internal pipeline programs
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4b_blue-shape.svg'
    image CB2, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4d_blue-key.svg'
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f966801791f1b026b0738_blue-shape.svg'
    image Metabolic, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4c_green-key.svg'
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a52_yellow-shape.svg'
    image Inflammation, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4f_yellow-key.svg'
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a49_coral-shape.svg'
    image Cancer, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4a_coral-key.svg'
    contentinfo
        StaticText Newsroom
        heading Press inquires
        StaticText Excited to share our story! Connect with us at the email below for media inquiries.
        link press@abalonebio.com Arrow right Arrow right, url='mailto:press@abalonebio.com?subject=Contact%20from%20website'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        link Home page, url='https://www.abalonebio.com/'
            image Home page, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899d1_iconlogo-footer.svg'
        StaticText Abalone Bio
        StaticText 1250, 45st. Ste 520,
        StaticText Emeryville, CA, USA, 94608
        link Platform, url='https://www.abalonebio.com/platform'
        link Pipeline, url='https://www.abalonebio.com/pipeline'
        link Partnerships, url='https://www.abalonebio.com/partnerships'
        link LinkedIn, url='https://www.linkedin.com/company/abalone-bio-inc/'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899cd_icon-linkedin.svg'
        link A product by Codon65 A product by Codon65, url='https://www.codon65.com/'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a59_sign-default.svg'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a58_sign-hover.svg'
        StaticText Abalone Bio © All rights reserved.
        StaticText ©
        StaticText 2024

Reasoning for action: To fulfill the user's request for information about Abalone Bio's capabilities and projects, I needed to navigate to the 'Pipeline' page by clicking on the 'Pipeline' link in the navigation. This step is sequential in the user's journey, as they are interested in exploring the available platforms and current projects before moving on to partnerships. By accessing the 'Pipeline' page, I will be able to gather the detailed information necessary for the user to evaluate collaboration or investment opportunities.

Action: click('57') # Click on the 'Pipeline' link to explore their current projects.

Change Description: The browser navigated from the 'Platform' page to the 'Pipeline' page of Abalone Bio, changing the focused URL to 'https://www.abalonebio.com/pipeline' and updating the content to include information about activating antibodies and their applications across multiple disease areas.

Screenshot before:Screenshot after:---

Step 3:

Url (before/after):

https://www.abalonebio.com/pipeline

https://www.abalonebio.com/partnerships

Content (before/after): 

RootWebArea Abalone Bio | Pipeline, focused, url='https://www.abalonebio.com/pipeline'
    banner
        [50] link Abalone Bio Abalone Bio, center=(468,36), url='https://www.abalonebio.com/'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a08_iconlogo-default.svg'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a07_iconlogo-hover.svg'
Show more 
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a06_iconlogo-click.svg'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a04_wordmark.svg'
        navigation
            [58] link Platform, center=(1203,36), url='https://www.abalonebio.com/platform'
            [59] link Pipeline, center=(1302,36), url='https://www.abalonebio.com/pipeline'
            [60] link Partnerships, center=(1414,36), url='https://www.abalonebio.com/partnerships'
            [61] link News, center=(1519,36), url='https://www.abalonebio.com/media'
    heading Pipeline
    heading Multiple disease areas uniquely unlocked by activating antibodies
    paragraph
        StaticText Our specific, activating antibodies address the liabilities of other drugs for challenging targets: they have the specificity that small molecules and peptides often don’t, and the activity that other antibodies typically lack. Antibodies have long half-lives, unlike some small molecules and peptides, making them very effective for chronic conditions. Antibodies also have the chemical and large structural complexity to better mimic large ligands, like chemokines, and interact with multiple parts of the target for effective activation.
    StaticText Specifically activate targets and target subpopulations to increase efficacy and reduce intolerable side effects
    StaticText ‍
    StaticText Activate hypertrophy to combat muscle loss during weight loss.
    StaticText Metabolic
    image Arrow, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a09_arrow-up.svg'
    StaticText Inflammation
    image Arrow, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a09_arrow-up.svg'
    StaticText Activate wound-healing to address disease causes, not just treat symptoms
    StaticText ‍
    StaticText Allosterically activate hydrophobic ligand responsive receptors from the outside of the cell, sidestepping problems of  hydrophobic drugs that bind orthosterically.
    StaticText Cancer
    image Arrow, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a09_arrow-up.svg'
    [104] div, center=(960,897), inner_text=Activate wound-healing to address disease causes, not just treat symptoms
‍
Allosterically activate hydrophobic ligand responsive receptors from the outside of the cell, sidestepping problems of  hydrophobic drugs that bind orthosterically.
    StaticText Locally recruit and activate tumor-killing T cells to tumors with chemokine receptor activators
    StaticText ‍
    StaticText Activate receptor internalization to expand the therapeutic windows of ADCs.
    StaticText Pipeline
    heading We have performed multiple discovery campaigns for partners and internal pipeline programs
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4b_blue-shape.svg'
    image CB2, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4d_blue-key.svg'
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673f966801791f1b026b0738_blue-shape.svg'
    image Metabolic, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4c_green-key.svg'
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a52_yellow-shape.svg'
    image Inflammation, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4f_yellow-key.svg'
    image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a49_coral-shape.svg'
    image Cancer, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a4a_coral-key.svg'
    contentinfo
        StaticText Newsroom
        heading Press inquires
        StaticText Excited to share our story! Connect with us at the email below for media inquiries.
        link press@abalonebio.com Arrow right Arrow right, url='mailto:press@abalonebio.com?subject=Contact%20from%20website'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        link Home page, url='https://www.abalonebio.com/'
            image Home page, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899d1_iconlogo-footer.svg'
        StaticText Abalone Bio
        StaticText 1250, 45st. Ste 520,
        StaticText Emeryville, CA, USA, 94608
        link Platform, url='https://www.abalonebio.com/platform'
        link Pipeline, url='https://www.abalonebio.com/pipeline'
        link Partnerships, url='https://www.abalonebio.com/partnerships'
        link LinkedIn, url='https://www.linkedin.com/company/abalone-bio-inc/'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899cd_icon-linkedin.svg'
        link A product by Codon65 A product by Codon65, url='https://www.codon65.com/'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a59_sign-default.svg'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a58_sign-hover.svg'
        StaticText Abalone Bio © All rights reserved.
        StaticText ©
        StaticText 2024

RootWebArea Abalone Bio | Partnerships, focused, url='https://www.abalonebio.com/partnerships'
    banner
        [48] link Abalone Bio Abalone Bio, center=(468,36), url='https://www.abalonebio.com/'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a08_iconlogo-default.svg'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a07_iconlogo-hover.svg'
Show more 
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a06_iconlogo-click.svg'
            image Abalone Bio, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a04_wordmark.svg'
        navigation
            [56] link Platform, center=(1203,36), url='https://www.abalonebio.com/platform'
            [57] link Pipeline, center=(1302,36), url='https://www.abalonebio.com/pipeline'
            [58] link Partnerships, center=(1414,36), url='https://www.abalonebio.com/partnerships'
            [59] link News, center=(1519,36), url='https://www.abalonebio.com/media'
    heading Partnerships
    image Illustration of a biological interaction with labeled components (VHH, scFV, Fab, Peptides, Proteins) leading to modulation effects., url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a6d_Graphic-10.svg'
    heading We discover functionally active antibody drugs for our partners’ challenging targets
    paragraph
        StaticText Using our platform and proprietary antibody libraries, we’ve discovered activating antibodies for multiple GPCRs. Let us create activators and modulators for your targets.
    paragraph
        StaticText We’re dedicated to expanding the impact of activating and modulating antibody therapeuitcs to as many targets and diseases as possible through key partnerships.
    StaticText Our partnerships
    heading Partnering with Abalone Bio
    heading Discovery partnerships
    paragraph
        StaticText Abalone Bio’s unique high-throughput platform creates antibodies that modulate target activity. While our internal pipeline is currently focused on agonists and positive modulators, we can also find negative modulators and inhibitors for your targets.
    heading Asset co-development partnerships
    paragraph
        StaticText We are developing antibody agonists against multiple targets spanning multiple indications including metabolic disease (including obesity), inflammation, and cancer. We are excited to develop these much-needed therapeutics with the right development and commercialization partners.
    StaticText Contact
    heading Let’s work together
    link bd@abalonebio.com Arrow right Arrow right, url='mailto:bd@abalonebio.com?subject=Contact%20from%20website'
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
        image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
    contentinfo
        StaticText Newsroom
        heading Press inquires
        StaticText Excited to share our story! Connect with us at the email below for media inquiries.
        link press@abalonebio.com Arrow right Arrow right, url='mailto:press@abalonebio.com?subject=Contact%20from%20website'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899e4_arrow-right.svg'
            image Arrow right, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899f5_arrow-right-hover.svg'
        link Home page, url='https://www.abalonebio.com/'
            image Home page, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899d1_iconlogo-footer.svg'
        StaticText Abalone Bio
        StaticText 1250, 45st. Ste 520,
        StaticText Emeryville, CA, USA, 94608
        link Platform, url='https://www.abalonebio.com/platform'
        link Pipeline, url='https://www.abalonebio.com/pipeline'
        link Partnerships, url='https://www.abalonebio.com/partnerships'
        link LinkedIn, url='https://www.linkedin.com/company/abalone-bio-inc/'
            image, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f899cd_icon-linkedin.svg'
        link A product by Codon65 A product by Codon65, url='https://www.codon65.com/'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a59_sign-default.svg'
            image A product by Codon65, url='https://cdn.prod.website-files.com/673e4ec5b5b3505435f8999c/673e4ec5b5b3505435f89a58_sign-hover.svg'
        StaticText Abalone Bio © All rights reserved.
        StaticText ©
        StaticText 2024

Reasoning for action: My reasoning for this action is that by clicking on the 'Partnerships' link in the navigation menu, I am directly accessing a page that is likely to contain valuable information about collaboration opportunities with Abalone Bio. This action aligns with the user's goal of exploring partnerships, which is a crucial aspect when evaluating potential collaboration or investment in biotechnology innovations.

Action: click('60') # Click on the 'Partnerships' link to explore their collaborations and partnerships.

Change Description: The browser navigated to the 'Partnerships' page of Abalone Bio, changing the focused section from 'Pipeline' to 'Partnerships', and updated the main heading and content to reflect information about the company's collaborations and commitment to developing therapeutic partnerships.

Screenshot before:Screenshot after:---